Coronavirus Update - 09th November 2020

We would like to reassure our customers that as England enters its second national lockdown period, we remain open for business and at full capacity as we have done since the start of this pandemic and fully comply with all government guidance on minimising the risks of COVID-19.

As the situation continues to evolve, we will keep all our customers and stakeholders informed of our activities through this web-page which is updated on a regular basis.

Our work and case studies

API Development Case Study

Challenge: Rapid development of a scalable route towards an analogue of a new drug substance, with definition of an optimal salt form for formulation Customer:

Thermal Rearrangement - Continuous Flow Case Study

Challenge: Thermal rearrangement of 7.5 kg of an API intermediate – A technically challenging and labour intensive process in batch with a typical yield of 50% and a poor impuri

Stable Isotope Labelling Case Study

Challenge: MPK and Bioanalysis need to quantify parent and metabolite drug concentrations in biological samples from non-clinical and clinical trials. Customer:

Analysis of Insulin Analogues Case Study

Challenge: A client has developed new product to fulfil an unmet patient need. Pivotal clinical studies require highly sensitive, precise measurement of multiple insulin analogues

Drug Substance Salt Selection Case Study

Challenge: To manufacture drug substance and screen a selection of corresponding pharmaceutically acceptable salt forms.  From the resulting salt forms, choose a candidate wh

Analytical & Microbiological Support to Clinical Research Unit

Challenge: Development and validation of analytical and microbiological methods for Intravenous (IV) products manufactured extemporaneously (EP) at Clinical Research Unit. Testing

Radiosynthesis via Chemically Unstable Intermediate

Challenge: Process chemistry route to API required hydrogenation, then salt formation. The hydrogenation product was chemically unstable until the salt was formed. On a large scal