Coronavirus Update - 07th August 2020

We would like to take this opportunity to thank our clients and staff for their continued support over this period of restricted movement. 

We remain open for business as usual and have started welcoming limited numbers of visitors to site

We fully comply with all government guidance on minimising the risks of COVID-19 and have published our risk assessment here

Our work and case studies

Challenge: Build and validate an assay to measure non-haem iron in tissues thereby supporting one of the pivotal objectives for a regulatory non-clinical safety study.

Customer:

UK Speciality-Pharma Company

Outcome:

A GLP-compliant assay for quantification of non-haem iron in liver, kidney and spleen was validated. Analysis of non-clinical samples was achieved. Results supported continued development of the molecule in question.

biochemical assays grpahs

  • Procedures for tissue extraction of non-haem iron were optimised and partnered with a colorimetric assay.
  • Following validation, the assay was used to support a non-clinical study: non-haem iron was detected in all tissues and exhibited a dose-response.
  • The data supported the aims of the study and proved the utility of a non-haem iron assay in a GLP setting.