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Drug Substance Equipment List

Key Equipment Type
Brand - Supplier
Qty
Comment
Standard
Reactor Vessels
24 L Double jacketed reaction vessel
Diehm
4
Borosilicate glass
GMP
24 L Single jacketed reaction vessel
Diehm
4
Borosilicate glass
GMP
10 L Single wall receiver
Diehm
4
Borosilicate glass
GMP
7 L Single wall header
Diehm
4
Borosilicate glass
GMP
7 L Single jacketed reaction vessel
Diehm
4
Borosilicate glass
GMP
7 L Single wall receiver
Diehm
1
Borosilicate glass
GMP
3 L Single wall header
Diehm
1
Borosilicate glass
GMP
7 L Single jacketed reaction vessel
Diehm
4
Borosilicate glass
nonGMP
7 L Single wall receiver
Diehm
2
Borosilicate glass
nonGMP
3 L Single wall header
Diehm
2
Borosilicate glass
nonGMP
Salamander
CRD
1
Hastelloy (Continuous)
nonGMP
Hcube
Thales nano
1
(Continuous)
nonGMP
FlowSyn
Uniqusis
1
(Continuous)
nonGMP
Trickle Bed Flow Hydrogenator
CRD
1
SS (to 100 Bar and 300 Deg. Cent.)
GMP
100 L Single jacketed Reaction vessel
De Dietrich
2
Borosilicate glass
GMP
Purification
Biotage Isolera
Biotage
1
10 – 340 g cartridges
nonGMP
Biotage Flash 150 L
Biotage
1
8 kg cartridges
GMP
Biotage Selekt
Biotage
2
10-1.5kg cartridges
nonGMP
Drying
Vacutherm oven VT6130 M-BL
Vacutherm
1
40 to 200 °C
GMP
Pope filter dryer
Pope
1
Stainless Steel
GMP
Mobile filter dryer
Aurora
1
Hastelloy (100g-15kg)
GMP
HPLC
HPLC Systems
Agilent/HP1000/1200
4
3 x 1100 1 x 1200
nonGMP
HPLC Detectors
Agilent
4
4 x UV
nonGMP
Temperature Control Units
Huber Unistat 912w
Huber
1
-90 to 180 °C
GMP
Huber Unistat 510w
Huber
1
-50 to 180 °C
GMP
Huber Unistat 430w
Huber
2
-40 to 180 °C
GMP
Huber Ministat 230
Huber
1
-40 to 180 °C
GMP
Huber Mnistat 240
Huber
1
-20 to 160 °C
GMP
Huber Ministat 230
Huber
2
-20 to 160 °C
nonGMP
Huber Mnistat 240
Huber
2
-20 to 160 °C
nonGMP
Correct as at 03-Feb-2020