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Scale-up Chemist

Date Posted: 1/11/2018
Application Close: 29/3/2019
Location: Arcinova - Alnwick
Description:

You will have the opportunity to work on a variety of pharmaceutical projects covering a range of synthetic organic chemistry. 

The key tasks of the position are:

  • Plan, perform and manage chemical syntheses in accordance with regulatory and company procedures.
  • Conduct route development and/or technology transfer studies in support of a range of scales. Taking into account scalability, safety and cost of goods for the proposed route.
  • Prepare cost estimates and client proposals in collaboration with Business Development. 
  • Act as a Project Manager for syntheses as assigned and function as a point of contact for clients, providing periodic updates, reports and archiving.
  • Perform in-process analytical testing where relevant and/or ensure that analytical, microbiological (where relevant) and materials science/spectroscopic testing needs are discussed and agreed with the onsite analytical team.
  • Ensure, where required, that laboratory work and associated documentation complies with GMP or other regulatory requirements, internal policies/procedures and client requirements.
  • Support manufacturing operations with shift cover as required. 

The successful candidate will either hold a PhD in synthetic organic chemistry or have a Chemistry degree with a minimum of one year’s experience in a Fine Chemical / Pharmaceutical / CMO background. Experience of scale up manufacture to 20 L would be an advantage, as would experience of GMP operations. You should be able to demonstrate good interpersonal and communication skills, both written and oral, and must be self-motivated.  A high level of personal integrity and commitment is essential, as is a flexible approach to new work challenges.