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stdClass Object ( [id] => 233 [title] => Arcinova hosts NEPIC Pharmaceutical Conference 2018 [alias] => arcinova-hosts-nepic-pharmaceutical-conference-2018 [title_alias] => [introtext] =>

Arcinova successfully hosts the NEPIC conference which discussed High Potency Processing. 

[language] => * [fulltext] =>

The challenges of high potency processing – and the innovations and solutions to help overcome them – were in the spotlight at The North East of England Process Industry Cluster (NEPIC) Pharmaceutical Conference 2018, which was held at our Alnwick site.

The conference, which took place on May 1, brought together an expert panel of speakers and industry professionals who provided insights into a number of aspects of high potency processing, including: categorisation; risk assessment; process development issues; creating a facility for HPAPI; manufacturers’ perspectives; and design and engineering issues.

NEPIC is a membership cluster organisation working with the chemical-using industries in the North East of England. It covers a broad sweep of chemistry-focussed industries including pharmaceuticals, biotechnology, petrochemicals, polymers and materials, fine and speciality chemicals and renewables. 

The day offered a variety of networking opportunities and a chance for delegates to build alliances in the pharmaceutical sector. 

Representatives of Arcinova, BPE, Fujifilm Diosynth Biotechnologies, Safebridge Consultants, YProTech, ProSys Sampling Systems, WH Partnership, Solo Containment, HPAPI Project Services and S3 Processing presented at the event. 

Paul Quigley, Head of API Development and Bioanalytical Services at Arcinova, presented on market drivers for highly potent Active Pharmaceutical Ingredients (APIs).This included pharma sales growth expectations in the next few years, and small molecule API trends and their role in driving pharmaceutical growth.

A panel discussion at the end of the session allowed speakers to share their knowledge and expertise on market trends, technical challenges and effective solutions. This was followed by a guided tour through our 15,000m2  facility. 

The conference was Philip Aldridge’s first event as the new CEO of NEPIC. He first joined the cluster in 2012 and specialised in supporting the pharmaceutical sector in the North East before taking up his new role as CEO.

Philip Aldridge, CEO of NEPIC, said: “I am delighted with the outcome of NEPIC’s pharmaceutical conference held at Arcinova’s Alnwick facility. We heard from a wide range of speakers covering the subject of high potency processing from a number of angles, which provided the large audience with a holistic view of an important pharmaceutical manufacturing trend. 

“The professional help we received from Arcinova staff and their excellent facilities contributed significantly to what was a very successful event. I was particularly pleased that a number of the world class speakers assembled said that this conference was better than most they had presented at recently covering this subject. 

“What NEPIC does best is to get business communities together to share best practice and make new business connections. I felt that this conference achieved this for a very important sector of the North East economy.”

Ian Shott, CEO of Arcinova, said: “At Arcinova, we understand the success of the North East pharmaceutical sector depends on regional organisations working together. We are very happy to have collaborated with NEPIC to help strengthen and promote the pharmaceutical sector in North East England and we were thrilled to welcome delegates to our site in Alnwick. As a business we are committed to helping the sector in the North East to grow and prosper.

“We saw specialists from the pharmaceutical sector sharing knowledge on high potency processing and bringing an outstanding level of technical expertise to the table, expertise that was shaped by real life experiences in industry. The panel discussion also opened up new debates and provided much food for thought around high potency processing and it is testimony to NEPIC’s strength as a cluster that delegates and speakers from across the UK attended the conference.”

The North East of England has a strong heritage in pharmaceutical manufacturing, capability and expertise. The region is home to over 1000 life science and healthcare companies that together employ 38,000 people, generate a combined turnover of £10.5 billion and contribute 33% of the UK’s pharmaceutical GDP.

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Arcinova successfully hosts the NEPIC conference which discussed High Potency Processing. 

)

Arcinova hosts NEPIC Pharmaceutical Conference 2018

The challenges of high potency processing – and the innovations and solutions to help overcome them – were in the spotlight at The North East of ...

Find Out More

stdClass Object ( [id] => 234 [title] => Arcinova increases GC-MS/MS capabilities with new system [alias] => arcinova-increases-gc-ms-ms-capabilities-with-new-system [title_alias] => [introtext] =>

We have doubled bionanalysis capability by investing in another GC-MS/MS system. 

[language] => * [fulltext] =>

We have installed a new Thermo Scientific™ TSQ™ Duo triple quadrupole GC-MS/MS system at our Alnwick site. 

The addition of this new system has allowed us to double our capacity in GC-MS as well as expand our analytical capabilities.  

The system is tailored to chromatographers and single quadrupole GC-MS users who need easy access to powerful new workflows through MS/MS and the ability to meet their current method requirements.  

It features selected reaction monitoring (SRM) which cuts through heavy matrix backgrounds for clear detection of target compounds.

Its Thermo Scientific™ TRACE™ 1300 Series gas chromatograph is configurable for headspace and liquid injection and allows us to address a huge variety of GC and GC-MS applications. 

This system is also effective in enabling us to streamline our operations with one data system for GC, autosampler and MS. It features Tracefinder an intelligent functionality which supports increased efficiency in our laboratories. 

Our site is also fully equipped with Agilent GC-MS with EI/CI Source and GERSTEL multi-purpose sampler with liquid and headspace capacity, providing us with extra capability when working with small volatile molecules.

Stuart McDougall, Bioanalysis Leader at Arcinova, said: “We are continuing to invest in state-of-the-art equipment to match our world class capabilities and expertise, and the Thermo Scientific™ TSQ™ Duo triple quadrupole GC-MS/MS system will play a key part in the expansion of our GC-MS services. 

“It will allow us to offer more capacity to clients and we’re delighted to now have this system at our disposal.”

For more information on our GC-MS services, click here

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We have doubled bionanalysis capability by investing in another GC-MS/MS system. 

)

Arcinova increases GC-MS/MS capabilities with new system

We have installed a new Thermo Scientific™ TSQ™ Duo triple quadrupole GC-MS/MS system at our Alnwick site. 

The addition of ...

Find Out More

stdClass Object ( [id] => 227 [title] => Arcinova strengthens leadership team with new appointment [alias] => arcinova-strengthens-leadership-team-with-new-appointment [title_alias] => [introtext] =>

Arcinova have a new Head of Regulatory, Technical and Administration Systems. 

[language] => * [fulltext] =>

Arcinova has appointed Rob Dungworth as our new Head of Regulatory, Technical and Administration Systems. 

Rob brings more than 25 years’ experience to Arcinova and will be overseeing our business operations. 

Rob studied Chemistry at the University of Huddersfield and has a Postgraduate Diploma in Industrial Pharmaceutical Sciences from Brighton University. 

Prior to joining Arcinova, he held Head of Quality Assurance roles with Sandoz, Leeds and Novartis in Horsham. He also held the positions of Head of Quality Assurance, Head of Production and Director of Operations at Sanofi-Aventis, Fawdon, Newcastle upon Tyne and most recently worked as Business Unit Director for GSK in Barnard Castle. 

In his new role as Head of Regulatory, Technical and Administration Systems for Arcinova, Rob will be responsible for managing the company’s information technology system and Human Resources function and ensuring Arcinova’s compliance with its legal obligations of cGxP. He will also play a key role in setting and shaping internal strategies. 

Commenting on his new role, Rob Dungworth said: “I am delighted to have been appointed as Head of Regulatory, Technical and Administration Systems at Arcinova. 

“The company has experienced major growth over the last two years and it’s an exciting time to be joining the team. 

“I’m looking forward to playing my part in driving the business forward and being part of the journey at Arcinova.”

Ian Shott, managing director of Arcinova, said: “We are delighted to be welcoming Rob to Arcinova. The specialist skills and capabilities he has developed through his long career in the pharmaceutical industry will be an immense asset to our team as the company grows. 

“It’s fantastic to be strengthening our team with new appointments following a period of growth for the company.”

 

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Arcinova have a new Head of Regulatory, Technical and Administration Systems. 

)

Arcinova strengthens leadership team with new appointment

Arcinova has appointed Rob Dungworth as our new Head of Regulatory, Technical and Administration Systems. 

Rob brings more than 25 years’ experience ...

Find Out More

stdClass Object ( [id] => 225 [title] => Arcinova receive grant for continuous processing technology [alias] => arcinova-receive-grant-for-continuous-processing-technology [title_alias] => [introtext] =>

Arcinova and University of Nottingham announce Innovate UK Grant.

[language] => * [fulltext] =>

Arcinova has announced the award of a £1.5 million Innovate UK grant for the development of new flexible modular manufacturing technologies; a project which is set to demonstrate the operating feasibility of world first innovative continuous production tools.

The project, which will span a three-year period, will be undertaken in collaboration with a team led by Professor Mike George, with Professors Pete Licence and Sir Martyn Poliakoff at the University of Nottingham. 

The aim of the project is to develop a continuous, flexible modular manufacturing technology platform which will enable Arcinova to handle increasingly complex chemistries with more discreet manufacturing steps. 

The platform will be used in manufacturing operations where manufacturing inventories need to be kept low and product purity needs to be maximized, where manufacturing throughput and efficiency are maintained at a high level and equipment changeover can be rapidly facilitated to cope with low batch numbers. 

The project outcome is set to position Arcinova as a world leader in defining continuous modular manufacturing technology for the support of new chemical entities (NCEs) development, scale up and manufacture.

The developed continuous modular manufacturing technology will be easily scalable, with a reduced manufacturing footprint when compared to more traditional, batch reactor approaches. The developed technologies will enable Arcinova to enhance manufacturing capacity and minimise inventories for highly reactive hazardous processes whereas for a batch process the reaction scale would be severely constrained

Arcinova is a leading provider of drug substance process development and scale up support for a global client base and has inherited a site which has been operating for over 30 years with a wealth of process chemistry, safety, engineering and manufacturing support skills and infrastructure, both in batch and continuous manufacture.

The developed flexible modular manufacturing technology platform will enhance our existing infrastructure in GMP and non GMP assets, which include 5-litre and 20-litre GMP vessel streams, and build on its current capabilities in continuous processing technology.

Ian Shott CBE, CEO of Arcinova said: “I have spent over 20 years championing the way that pharmaceuticals are manufactured in the UK and have been an enthusiastic advocate for new manufacturing technologies including continuous manufacturing and synthetic biology as enablers for new and radically different pharmaceutical production approaches. 

“This focus on improving productivity is laid out in the 2017 whitepaper on UK Industrial Strategy. I was delighted to learn of our successful Innovate UK grant which will enable Arcinova to offer a compelling, innovative and simplified route to high grade pharmaceutical manufacture.”

Mike George, Professor of Chemistry at the University of Nottingham, said: “My colleagues and I at Nottingham are firmly convinced that flow chemistry can transform chemical manufacture in the UK and this partnership with Arcinova is an opportunity to turn our vision into reality.”

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Arcinova and University of Nottingham announce Innovate UK Grant.

)

Arcinova receive grant for continuous processing technology

Arcinova has announced the award of a £1.5 million Innovate UK grant for the development of new flexible modular manufacturing technologies; a project which is ...

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stdClass Object ( [id] => 224 [title] => NEPIC Pharmaceutical Conference: High Potency Processing [alias] => arcinova-collaborates-with-nepic-to-host-networking-event [title_alias] => [introtext] =>

Arcinova collaborates with NEPIC to support North East England’s pharmaceutical sector. 

[language] => * [fulltext] =>

We are delighted to be hosting the North East of England Process Industry Cluster (NEPIC) Pharmaceutical Conference, which focuses on High Potency Processing.

The event will take place at our site in Alnwick, UK on Tuesday 1st May, 2018.

NEPIC is a membership cluster organisation working with the chemical-using industries in the North East of England. It covers a broad sweep of chemistry-focussed industries including pharmaceuticals, biotechnology, petrochemicals, polymers & materials, fine & speciality chemicals and renewables.

This conference will cover a number of aspects of high potency processing, including categorisation, process development issues, manufacturers’ perspectives, equipment and engineering design issues. 

The one-day event offers a wide variety of networking opportunities and gives delegates a chance to build alliances in the pharmaceutical sector, and share their knowledge and expertise about market trends and effective solutions. 

Guests will also benefit from a tour of our 15,000 sqm facility and will hear from an expert panel of speakers who will provide insights into high potency processing. 

Presentations will include:  

Market Trends for HP Medicines – Paul Quigley, Arcinova

HP medicines categorisation – Martin Axon, Safebridge Consultants

‘Software Issues’ (people) associated with HP Processing – Justin Mason-Homes, HPAPI Project Services

Design and operation of a HP biologics facility – Fujifilm Diosynth Biotechnologies   

Issues around process development for HP medicines – Stuart Brown, YProTech

Continuous Manufacturing for Oral Solid Dose HP Pharmaceuticals – Steve Boswell, S3 Processing

BPE Engineering – Details coming soon

Cost effective facility HP design – Richard Anderson, WH Partnership

Equipment for HP Processing – Andy Parry, ProSys Sampling Systems

The use of Flex-Film isolators for HP manufacturing – Martyn Ryder, Solo Containment

Ian Shott, Managing Director at Arcinova said: “We are delighted to be working with the North East of England Process Industry Cluster to help strengthen and promote the pharmaceutical sector in North East England, and it gives us great pleasure to host this conference here in Northumberland. 

“We look forward to welcoming delegates to our site in Alnwick and to seeing specialists from the pharmaceutical sector sharing their knowledge and expertise on high potency processing.”

To book your place visit the NEPIC website.

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Arcinova collaborates with NEPIC to support North East England’s pharmaceutical sector. 

)

NEPIC Pharmaceutical Conference: High Potency Processing

We are delighted to be hosting the North East of England Process Industry Cluster (NEPIC) Pharmaceutical Conference, which focuses on High Potency Processing.

<...

Find Out More

stdClass Object ( [id] => 215 [title] => Celebrating two years in business [alias] => celebrating-two-years-in-business [title_alias] => [introtext] =>

Arcinova announces substantial growth in turnover and a major increase in staff numbers.

[language] => * [fulltext] =>

Arcinova was launched in February 2016, following the acquisition of the Covance site in Alnwick, by Arc Trinova Limited, a new company formed by Ian Shott and Paul Ryan, owners of Shott Trinova LLP. Our site was formerly owned by Sanofi, before being bought by Covance in 2010.

Arcinova’s year on year turnover grew by 60 per cent and our client numbers have increased from 50 to more than 120 in less than 24 months. 

We have almost doubled our workforce in the last two years and have recently recruited new scientists into our Bioanalysis, API and CMC teams.

Our site has seen substantial additional investment since the launch of Arcinova as a company. We’ve invested heavily in new drug formulation and small volume API manufacturing equipment – including the introduction of two 20 litre capacity streams and one five litre stream - and we have extended our existing CMC and bioanalysis capabilities. 

Ian Shott, CEO of Arcinova said: “It’s heartening to see that in just two years, we’ve built on the experience of the site’s existing team and our world-class facilities in Alnwick to grow our workforce, extend our capabilities and further strengthen our ability to serve the global pharmaceutical and biotechnology communities. 

“Our specialist teams are making a real difference to drug development projects across the world and we are witnessing growing demand for our services. 

“It has been an exciting journey so far and we’re looking forward to what the future holds for Arcinova.” 

Read the full article online at the Chronicle Live

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Arcinova announces substantial growth in turnover and a major increase in staff numbers.

)

Celebrating two years in business

Arcinova was launched in February 2016, following the acquisition of the Covance site in Alnwick, by Arc Trinova Limited, a new company formed by Ian ...

Find Out More

stdClass Object ( [id] => 218 [title] => Quality Control specialist joins Arcinova’s management team [alias] => arcinova-shows-significant-growth-after-successful-two-years-2 [title_alias] => [introtext] =>

We have appointed Daniel Bell as our new Head of Quality Control. 

[language] => * [fulltext] =>

Daniel will be responsible for overseeing all areas of quality assurance. He brings more than 15 years’ experience to the Arcinova team.

Daniel studied Pharmaceutical Chemistry at Sheffield Hallam University and began his career as a Stability Analyst at Merck, Sharp and Dohme.

Following this, he moved to Sanofi-Aventis, where he worked in laboratory, production and process improvement roles, before joining Piramal Enterprises Limited, where he held both Stability Team Leader and Quality Control Manager positions. 

Daniel left Piramal to setup a new laboratory in County Durham, for UK-based Quantum Pharma as Quality Control Manager, this laboratory was approved by the MHRA in 2015. Daniel was then promoted to Head of Operational Quality and Quality Control, where he managed numerous quality functions over multiple sites, before moving to Arcinova. 

Commenting on his new role, Daniel said: “I am thrilled to be appointed as the new head of Quality Control at Arcinova. The company has built up an excellent reputation, thanks to its world class scientific expertise and facilities, and is forging ahead with an ambitious growth strategy. 

“I’m looking forward to bringing my experience in Quality Control to bear for Arcinova and to be playing my part in the company’s evolution.”

Ian Shott, managing director of Arcinova, said: “We are delighted to have a candidate of Daniel’s calibre joining our team. 

“He brings a wealth of expertise to the company and will play an instrumental role in overseeing our internal procedures and processes, which will prove highly valuable for us as we continue to grow.”

 

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We have appointed Daniel Bell as our new Head of Quality Control. 

)

Quality Control specialist joins Arcinova’s management team

Daniel will be responsible for overseeing all areas of quality assurance. He brings more than 15 years’ experience to the Arcinova team.

Daniel ...

Find Out More

stdClass Object ( [id] => 219 [title] => New additions to the Arcinova Bioanalysis team [alias] => more-new-additions-to-our-bioanalysis-team [title_alias] => [introtext] =>

Due to growth, our Bioanalysis team continues to expand with two new recruits.

[language] => * [fulltext] =>

We’ve bolstered our bioanalysis team in response to increased demand for the specialist services we offer. 

We’ve appointed Connor Walker and Paige Bellis as bioanalysts as part of our on-going recruitment drive.  

Connor and Paige will be supporting the bioanalysis team on the delivery of a range of services including Chromatographic Services (LC-MS), Inductively Coupled Plasma – Mass Spectrometry (ICP-MS), Gas Chromatography – Mass Spectrometry (GC-MS), Accurate Mass Spectrometry, In Vitro Assays and Bespoke Biochemical Assays and Metabolite Identification Studies.

The two new recruits are recent graduates of Northumbria University, where they studied Biomedical Sciences. Connor’s experience includes a placement at Institute of Genetic Medicine at the International Centre for Life in Newcastle, where he worked as a trainee biomedical scientist. Paige spent time as a laboratory technician at analytical laboratory Derwentside Environmental Testing Services before joining us.  The pair join three new bioanalysts – Polly Wight, Liam Burns and Jenny Baker – who joined us in 2017 as part of the expansion of the bioanalysis team. 

Commenting on her new role, Paige Bellis, who is from Hebburn, South Tyneside, said: “I’d always wanted to work in the pharmaceutical sector: Arcinova offered a brilliant opportunity to do this. It’s a really welcoming, friendly environment here and I’m looking forward to developing my skills and supporting the bioanalysis team on some really exciting projects.” 

Connor Walker, who is originally from Northumberland added: “I’ve seen the growth of Arcinova over the last two years and it seemed like exactly the right place in which to progress my career. To have a company of this size and capabilities in the heart of Northumberland is fantastic.”

Stuart McDougall, Bioanalysis Leader at Arcinova, said: “The growth of our bioanalytical services is continuing at a rapid rate, in part due to large pharmaceutical companies outsourcing specialist services such as ICP-MS and GC-MS. By recruiting Connor and Paige, we’re both strengthening our current team and building for our future – and we’re delighted to be welcoming them on board at what is an exciting time for Arcinova.”

Ian Shott, Managing Director, commented: “We’re proud to be able to offer opportunities for talented graduates here in North East England – and to help them further their careers as scientists. I’m sure that Paige and Connor have a very bright future here at Arcinova, a place from which they can support the work of pharmaceutical and biotech firms across the globe – and make a real impact.”

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Due to growth, our Bioanalysis team continues to expand with two new recruits.

)

New additions to the Arcinova Bioanalysis team

We’ve bolstered our bioanalysis team in response to increased demand for the specialist services we offer. 

We’ve appointed Connor ...

Find Out More

stdClass Object ( [id] => 201 [title] => Prize-winning performance from Luke [alias] => prize-winning-performance-from-luke [title_alias] => [introtext] =>

New CMC recruit Luke Robinson, has been awarded the Agilent prize for Excellence in Pharmaceutical Analysis. 

[language] => * [fulltext] =>

Luke Robinson, an analytical scientist in our CMC team, has won a major national award.

Luke, a Biopharmaceutical Science graduate from The University of Sunderland – who joined Arcinova this summer – has been awarded the Agilent prize for Excellence in Pharmaceutical Analysis.  This was in recognition of him achieving top mark in his final year Advanced Analytical Techniques module. 

The prize was presented to Luke at our Alnwick site on November 22nd, 2017. 

He also achieved a first class honours mark for his final year project in which he used LC-MS to investigate trace level unknown impurities in aspirin products. Away from his analytical work, Luke also won the Fujifilm Prize for achieving the highest mark in the Metabolomics and Proteomics module.

In addition, in the summer of 2016, Luke was awarded a bursary for an eight-week summer studentship, funded by the Chromatographic Society, through its joint summer studentship scheme with The British Mass Spectrometry Society (BMSS) and the Royal Society of Chemistry separations group. 

The Chromatographic Society is a UK registered charity founded in 1946, which aims to promote and disseminate knowledge on all aspects of chromatography and related separation techniques.

The studentships are focused on involving the student in scientific research resulting in a report, which may be shared via the society's publications and associated websites. Many studentships have led to academic publications and presentations. 

Part of Luke’s work on optimised peak capacity in gradients using UHPLC (Ultra-high-performance liquid chromatography) and HPLC (High-performance liquid chromatography). It was presented at The Chromatography Society meeting in Sandwich and a publication is in preparation, which is based on this work and other undergraduate work at the university. 

Ian Shott, Managing Director of Arcinova said: “We are thrilled that Luke has been recognised for his incredible academic achievements and would like to congratulate him on his success.”

Martin Gray, Head of CMC at Arcinova, added: “Luke is an outstanding young scientist and we’re delighted that he is now part of the team here at Arcinova.”

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New CMC recruit Luke Robinson, has been awarded the Agilent prize for Excellence in Pharmaceutical Analysis. 

)

Prize-winning performance from Luke

Luke Robinson, an analytical scientist in our CMC team, has won a major national award.

Luke, a Biopharmaceutical Science graduate from The ...

Find Out More