In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation

A cheap and operationally convenient method for chemoselective conjugate hydrogenation via heterogeneous catalysis has been developed utilising continuous flow. The sustainability features of the methodology were assessed through the green metric system and confirmed that the process can be considered green. The results of the study are an important milestone for the FLOWINOVA project, which aims to develop innovative continuous processes by first intent to significantly reduce the time and cost associated with drug development, scale-up and manufacture.
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